Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000004615Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (284 aa)    
Predicted Functional Partners:
nme9
NME/NM23 family member 8; Belongs to the NDK family.
    
 
 0.633
pla2g4a
Phospholipase A2.
     
 0.618
ENSACLP00000017156
WD repeat domain 90.
    
 
 0.588
ripk4
Receptor-interacting serine-threonine kinase 4.
    
 0.550
tonsl
Tonsoku-like, DNA repair protein.
    
  0.528
ENSACLP00000005906
Relaxin family peptide receptor 2a.
    
 0.514
lgr5
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
 0.514
ENSACLP00000017254
Relaxin family peptide receptor 1.
    
 0.514
lgr4
Leucine-rich repeat containing G protein-coupled receptor 4.
    
 0.514
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.495
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.