STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000004615Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (284 aa)    
Predicted Functional Partners:
pla2g4a
Phospholipase A2.
    
 0.656
ripk4
Receptor-interacting serine-threonine kinase 4.
    
 0.614
chek2
Checkpoint kinase 2.
    
0.548
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
  0.536
RPS27A
Ribosomal protein S27a.
    
  0.515
CASK
Uncharacterized protein; Belongs to the MAGUK family.
   
 
0.514
LOC113015779
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
 
0.514
mad1l1
Mitotic arrest deficient 1 like 1.
    
 0.512
becn1
Beclin 1, autophagy related.
    
 0.511
SLC39A3
Solute carrier family 39 member 3.
    
 0.510
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.