Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ptpreReceptor-type tyrosine-protein phosphatase. (695 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.950
ptpra
Receptor-type tyrosine-protein phosphatase alpha.
    
   0.909
LOC113022260
Carbonic anhydrase XVI b.
    
 0.851
LOC113014322
Protein tyrosine phosphatase receptor type Ua.
    
 0.835
LOC113031390
Protein tyrosine phosphatase receptor type Ub.
    
 0.835
PTPN14
Protein tyrosine phosphatase non-receptor type 14.
    
 
 0.828
ENSACLP00000027049
SLIT and NTRK-like family, member 2.
    
 0.769
IL1RAP
Interleukin 1 receptor accessory protein.
    
 0.766
LOC113008404
SLIT and NTRK-like family, member 5b.
    
  0.689
LOC113011806
SLIT and NTRK-like family, member 3b.
    
  0.689
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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