| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSACLP00000016968 | LOC113018890 | ENSACLP00000016968 | ENSACLP00000017481 | Uncharacterized protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.585 |
| ENSACLP00000016968 | adss1 | ENSACLP00000016968 | ENSACLP00000004638 | Uncharacterized protein. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.949 |
| ENSACLP00000016968 | atic | ENSACLP00000016968 | ENSACLP00000031240 | Uncharacterized protein. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.979 |
| ENSACLP00000016968 | gart | ENSACLP00000016968 | ENSACLP00000036327 | Uncharacterized protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ENSACLP00000016968 | gmpr | ENSACLP00000016968 | ENSACLP00000022677 | Uncharacterized protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.585 |
| ENSACLP00000016968 | impdh2 | ENSACLP00000016968 | ENSACLP00000027493 | Uncharacterized protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.593 |
| ENSACLP00000017004 | LOC113018890 | ENSACLP00000017004 | ENSACLP00000017481 | Adenylosuccinate lyase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.585 |
| ENSACLP00000017004 | adss1 | ENSACLP00000017004 | ENSACLP00000004638 | Adenylosuccinate lyase. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.949 |
| ENSACLP00000017004 | atic | ENSACLP00000017004 | ENSACLP00000031240 | Adenylosuccinate lyase. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.979 |
| ENSACLP00000017004 | gart | ENSACLP00000017004 | ENSACLP00000036327 | Adenylosuccinate lyase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ENSACLP00000017004 | gmpr | ENSACLP00000017004 | ENSACLP00000022677 | Adenylosuccinate lyase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.585 |
| ENSACLP00000017004 | impdh2 | ENSACLP00000017004 | ENSACLP00000027493 | Adenylosuccinate lyase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.593 |
| ENSACLP00000017042 | LOC113018890 | ENSACLP00000017042 | ENSACLP00000017481 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.585 |
| ENSACLP00000017042 | adss1 | ENSACLP00000017042 | ENSACLP00000004638 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.949 |
| ENSACLP00000017042 | atic | ENSACLP00000017042 | ENSACLP00000031240 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.979 |
| ENSACLP00000017042 | gart | ENSACLP00000017042 | ENSACLP00000036327 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ENSACLP00000017042 | gmpr | ENSACLP00000017042 | ENSACLP00000022677 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.585 |
| ENSACLP00000017042 | impdh2 | ENSACLP00000017042 | ENSACLP00000027493 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.593 |
| ENSACLP00000017095 | LOC113018890 | ENSACLP00000017095 | ENSACLP00000017481 | Uncharacterized protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.585 |
| ENSACLP00000017095 | adss1 | ENSACLP00000017095 | ENSACLP00000004638 | Uncharacterized protein. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.949 |
STRING v12.5 is now available!
