Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FIGNL2Fidgetin like 2. (688 aa)    
Predicted Functional Partners:
ist1
IST1 factor associated with ESCRT-III.
    
 0.928
ENSACLP00000035637
UBX domain-containing protein 7.
   
 0.877
c23h1orf112
Si:dkey-97o5.1.
   
 0.855
nme9
NME/NM23 family member 8; Belongs to the NDK family.
   
 0.801
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.798
spidr
Uncharacterized protein.
    
 0.797
ENSACLP00000017156
WD repeat domain 90.
    
 
 0.781
chmp1a
Charged multivesicular body protein 1A.
    
 0.778
chmp1b
Chromatin modifying protein 1B.
    
 0.778
LOC113033874
Uncharacterized protein.
    
 0.778
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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