Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
dhtkd1Dehydrogenase E1 and transketolase domain containing 1. (923 aa)    
Predicted Functional Partners:
DLST
Dihydrolipoamide S-succinyltransferase.
 
 0.990
LOC113012207
Dihydrolipoamide S-succinyltransferase.
 
 0.990
dld
Dihydrolipoyl dehydrogenase.
  
 0.969
suclg1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.960
suox
Sulfite oxidase.
   
  
 0.937
dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.928
GCDH
Glutaryl-CoA dehydrogenase b.
  
 
 0.926
LOC113023703
Glutaryl-CoA dehydrogenase a.
  
 
 0.926
sdha
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.924
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.914
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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