Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
plekha8Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8. (562 aa)    
Predicted Functional Partners:
ENSACLP00000029920
MNAT1 component of CDK activating kinase.
      
 0.662
trip4
Thyroid hormone receptor interactor 4.
      
 0.655
tmtc4
Transmembrane O-mannosyltransferase targeting cadherins 4.
      
 0.655
cope
Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family.
   
    0.651
rspry1
Ring finger and SPRY domain containing 1.
      
 0.622
gpatch3
G patch domain containing 3.
      
 0.615
ENSACLP00000029276
Uncharacterized protein.
      
 0.612
eaf1
ELL associated factor 1.
      
 0.610
snx20
Sorting nexin 20.
      
 0.571
sec24d
SEC24 homolog D, COPII coat complex component.
    
   0.567
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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