Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)    
Predicted Functional Partners:
ENSACLP00000018362
Serine/threonine-protein kinase TOR.
    
 0.980
pdpk1
3-phosphoinositide dependent protein kinase 1b.
   
 0.979
mdm2
MDM2 proto-oncogene.
    
 0.974
ENSACLP00000030835
TSC complex subunit 2.
    
 0.970
akt1s1
AKT1 substrate 1 (proline-rich).
   
 0.965
LOC113012253
Fork-head domain-containing protein.
    
 0.961
foxo4
Forkhead box O4.
    
 0.961
foxo3
Forkhead box O3b.
    
 0.961
nos1
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.961
LOC113036917
Forkhead box O1 a.
    
 0.961
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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