Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113010947SH3-domain GRB2-like 1a. (369 aa)    
Predicted Functional Partners:
sh3kbp1
SH3-domain kinase binding protein 1.
    
  0.936
cd2ap
CD2-associated protein.
    
  0.927
sh3d21
SH3 domain containing 21.
    
  0.927
LOC113010022
Receptor protein-tyrosine kinase.
    
 0.908
LOC113029559
Receptor protein-tyrosine kinase.
    
 0.908
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase.
    
  0.883
ENSACLP00000003287
Synaptojanin 1.
    
 
 0.882
LOC113026105
Tyrosine-protein kinase receptor.
    
  0.882
igf1r
Tyrosine-protein kinase receptor.
    
  0.882
pdgfra
Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
     
  0.872
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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