Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC113013067Signal transducer and activator of transcription. (769 aa)    
Predicted Functional Partners:
jak1
Tyrosine-protein kinase.
   
 0.978
tyk2
Tyrosine-protein kinase.
   
 0.975
LOC113006843
Tyrosine-protein kinase.
   
 0.975
LOC113021295
Erythropoietin receptor.
    
 0.954
LOC113033249
Tyrosine-protein kinase.
   
 0.950
LOC113025906
Tyrosine-protein kinase.
   
 0.950
prlr
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily.
    
 0.944
socs5
Suppressor of cytokine signaling 5b.
    
 0.944
LOC113021131
E1A binding protein p300 b.
    
 0.937
LOC113027597
E1A binding protein p300 a.
    
 0.937
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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