ENSACLP00000004817 protein (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ENSACLP00000004817

Striatin interacting protein 2. (765 aa)

Predicted Functional Partners:

LOC113007291-2

0.935

slmap

0.923

ENSACLP00000003704

0.907

STRN

0.907

LOC113036096

0.887

ENSACLP00000013574

0.885

LOC113021954

0.885

RNF8

0.880

strn3

0.878

LOC113013057

0.869

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000003704	ENSACLP00000004817	ENSACLP00000003704	ENSACLP00000004817	Striatin, calmodulin binding protein.	Striatin interacting protein 2.	0.907
ENSACLP00000003704	ENSACLP00000013574	ENSACLP00000003704	ENSACLP00000013574	Striatin, calmodulin binding protein.	CTTNBP2 N-terminal like b.	0.861
ENSACLP00000003704	LOC113007291-2	ENSACLP00000003704	ENSACLP00000034978	Striatin, calmodulin binding protein.	MOB family member 4, phocein.	0.901
ENSACLP00000003704	LOC113013057	ENSACLP00000003704	ENSACLP00000039187	Striatin, calmodulin binding protein.	Uncharacterized protein.	0.787
ENSACLP00000003704	LOC113021954	ENSACLP00000003704	ENSACLP00000029559	Striatin, calmodulin binding protein.	CTTNBP2 N-terminal like a.	0.844
ENSACLP00000003704	LOC113036096	ENSACLP00000003704	ENSACLP00000027786	Striatin, calmodulin binding protein.	Protein phosphatase 2, regulatory subunit A, beta b.	0.869
ENSACLP00000003704	RNF8	ENSACLP00000003704	ENSACLP00000035704	Striatin, calmodulin binding protein.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.842
ENSACLP00000003704	slmap	ENSACLP00000003704	ENSACLP00000013627	Striatin, calmodulin binding protein.	Sarcolemma associated protein a.	0.874
ENSACLP00000004817	ENSACLP00000003704	ENSACLP00000004817	ENSACLP00000003704	Striatin interacting protein 2.	Striatin, calmodulin binding protein.	0.907
ENSACLP00000004817	ENSACLP00000013574	ENSACLP00000004817	ENSACLP00000013574	Striatin interacting protein 2.	CTTNBP2 N-terminal like b.	0.885
ENSACLP00000004817	LOC113007291-2	ENSACLP00000004817	ENSACLP00000034978	Striatin interacting protein 2.	MOB family member 4, phocein.	0.935
ENSACLP00000004817	LOC113013057	ENSACLP00000004817	ENSACLP00000039187	Striatin interacting protein 2.	Uncharacterized protein.	0.869
ENSACLP00000004817	LOC113021954	ENSACLP00000004817	ENSACLP00000029559	Striatin interacting protein 2.	CTTNBP2 N-terminal like a.	0.885
ENSACLP00000004817	LOC113036096	ENSACLP00000004817	ENSACLP00000027786	Striatin interacting protein 2.	Protein phosphatase 2, regulatory subunit A, beta b.	0.887
ENSACLP00000004817	RNF8	ENSACLP00000004817	ENSACLP00000035704	Striatin interacting protein 2.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.880
ENSACLP00000004817	STRN	ENSACLP00000004817	ENSACLP00000035935	Striatin interacting protein 2.	Striatin.	0.907
ENSACLP00000004817	slmap	ENSACLP00000004817	ENSACLP00000013627	Striatin interacting protein 2.	Sarcolemma associated protein a.	0.923
ENSACLP00000004817	strn3	ENSACLP00000004817	ENSACLP00000024861	Striatin interacting protein 2.	Striatin, calmodulin binding protein 3.	0.878
ENSACLP00000013574	ENSACLP00000003704	ENSACLP00000013574	ENSACLP00000003704	CTTNBP2 N-terminal like b.	Striatin, calmodulin binding protein.	0.861
ENSACLP00000013574	ENSACLP00000004817	ENSACLP00000013574	ENSACLP00000004817	CTTNBP2 N-terminal like b.	Striatin interacting protein 2.	0.885