Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
spint1Serine peptidase inhibitor, Kunitz type 1 a. (506 aa)    
Predicted Functional Partners:
hgfac
HGF activator.
    
 0.941
mst1
Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.713
LOC113009437
Hepatocyte growth factor a; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.713
hgf
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.713
LOC113013415
Suppression of tumorigenicity 14b.
    
 0.659
ENSACLP00000017816
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.659
ENSACLP00000018009
Uncharacterized protein.
    
 0.659
st14
Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix.
    
 0.659
ENSACLP00000003108
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
      
 0.655
ENSACLP00000031218
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
      
 0.644
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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