Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (731 aa)    
Predicted Functional Partners:
ENSACLP00000014013
EF-hand calcium binding domain 2.
    
 
 0.575
LOC113010523
Kruppel like factor 6.
    
 
 0.530
klf6
Kruppel-like factor 6a.
    
 
 0.530
ahrr
Uncharacterized protein.
      
 0.509
pbk
PDZ binding kinase.
      
 0.505
aifm1
Apoptosis inducing factor mitochondrion associated 1.
   
  0.496
trip12
Thyroid hormone receptor interactor 12.
    
 
 0.491
ENSACLP00000004294
Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
     
 0.485
LOC113035495
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
     
 0.485
LOC113007418
RAN binding protein 2.
    
  0.478
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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