Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113016435Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)    
Predicted Functional Partners:
fgfr2
Fibroblast growth factor receptor.
    
 0.948
fgfr3
Fibroblast growth factor receptor.
    
 0.941
ENSACLP00000023118
Fibroblast growth factor receptor 4; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.941
LOC113033119
Fibroblast growth factor receptor.
    
 0.941
ENSACLP00000029128
Uncharacterized protein.
    
 0.941
ENSACLP00000029170
Uncharacterized protein.
    
 0.918
LOC113026317
Fibroblast growth factor receptor.
    
 0.918
ENSACLP00000013202
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.914
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.914
pdgfra
Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.913
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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