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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smpdl3aAcid sphingomyelinase-like phosphodiesterase. (442 aa)    
Predicted Functional Partners:
ENSACLP00000035355
Niemann-Pick disease, type C2.
   
 
  0.679
brinp1
Bone morphogenetic protein/retinoic acid inducible neural-specific 1.
      
 0.576
LOC113006988
Tetratricopeptide repeat domain 9C.
      
 0.538
cdc40
Cell division cycle 40 homolog (S. cerevisiae).
      
 0.506
btbd10
BTB (POZ) domain containing 10b.
      
 0.469
LOC113025164
BTB (POZ) domain containing 10a.
      
 0.469
LOC113015979
Uncharacterized protein.
      
 0.465
LOC113026591
Sulfide quinone oxidoreductase.
      
 0.439
ENSACLP00000032605
Pyr_redox_2 domain-containing protein.
      
 0.439
ccn6
Cellular communication network factor 6.
      
 0.404
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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