VAV1 protein (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

VAV1

Vav guanine nucleotide exchange factor 1. (786 aa)

Predicted Functional Partners:

grb2

0.913

RAC1

0.905

LOC113022989

0.905

LOC113027755

0.898

LOC113020808

0.898

LOC113020809

0.898

LOC113020810

0.898

LOC113034959

0.890

ENSACLP00000016464

0.846

syk

0.846

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000016464	LOC113020808	ENSACLP00000016464	ENSACLP00000041414	Tyrosine-protein kinase.	Uncharacterized protein.	0.501
ENSACLP00000016464	LOC113020809	ENSACLP00000016464	ENSACLP00000041415	Tyrosine-protein kinase.	Uncharacterized protein.	0.501
ENSACLP00000016464	LOC113020810	ENSACLP00000016464	ENSACLP00000041416	Tyrosine-protein kinase.	Uncharacterized protein.	0.501
ENSACLP00000016464	LOC113022989	ENSACLP00000016464	ENSACLP00000036531	Tyrosine-protein kinase.	Cell division cycle 42.	0.464
ENSACLP00000016464	LOC113027755	ENSACLP00000016464	ENSACLP00000001078	Tyrosine-protein kinase.	Rac family small GTPase 3b.	0.501
ENSACLP00000016464	LOC113034959	ENSACLP00000016464	ENSACLP00000026687	Tyrosine-protein kinase.	B cell linker.	0.925
ENSACLP00000016464	RAC1	ENSACLP00000016464	ENSACLP00000021643	Tyrosine-protein kinase.	Rac family small GTPase 1.	0.501
ENSACLP00000016464	VAV1	ENSACLP00000016464	ENSACLP00000004964	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 1.	0.846
ENSACLP00000016464	grb2	ENSACLP00000016464	ENSACLP00000027361	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2b.	0.820
LOC113020808	ENSACLP00000016464	ENSACLP00000041414	ENSACLP00000016464	Uncharacterized protein.	Tyrosine-protein kinase.	0.501
LOC113020808	LOC113022989	ENSACLP00000041414	ENSACLP00000036531	Uncharacterized protein.	Cell division cycle 42.	0.704
LOC113020808	LOC113034959	ENSACLP00000041414	ENSACLP00000026687	Uncharacterized protein.	B cell linker.	0.484
LOC113020808	VAV1	ENSACLP00000041414	ENSACLP00000004964	Uncharacterized protein.	Vav guanine nucleotide exchange factor 1.	0.898
LOC113020808	grb2	ENSACLP00000041414	ENSACLP00000027361	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.618
LOC113020808	syk	ENSACLP00000041414	ENSACLP00000033853	Uncharacterized protein.	Tyrosine-protein kinase.	0.501
LOC113020809	ENSACLP00000016464	ENSACLP00000041415	ENSACLP00000016464	Uncharacterized protein.	Tyrosine-protein kinase.	0.501
LOC113020809	LOC113022989	ENSACLP00000041415	ENSACLP00000036531	Uncharacterized protein.	Cell division cycle 42.	0.704
LOC113020809	LOC113034959	ENSACLP00000041415	ENSACLP00000026687	Uncharacterized protein.	B cell linker.	0.484
LOC113020809	VAV1	ENSACLP00000041415	ENSACLP00000004964	Uncharacterized protein.	Vav guanine nucleotide exchange factor 1.	0.898
LOC113020809	grb2	ENSACLP00000041415	ENSACLP00000027361	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.618