Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpvlCarboxypeptidase vitellogenic like; Belongs to the peptidase S10 family. (480 aa)    
Predicted Functional Partners:
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
   0.873
ENSACLP00000033251
2-epi-5-epi-valiolone synthase.
    
   0.858
alg5
ALG5 dolichyl-phosphate beta-glucosyltransferase.
   
   0.818
LOC113023368
Carboxypeptidase; Belongs to the peptidase S10 family.
   
 
 0.815
ctsa
Carboxypeptidase; Belongs to the peptidase S10 family.
   
 
 0.815
dctn2
Dynactin 2 (p50).
    
   0.811
has3
Hyaluronan synthase 3.
   
 
 0.796
has2
Hyaluronan synthase 2.
   
 
 0.796
has1
Hyaluronan synthase 1.
   
 
 0.796
pgap1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi.
    
 
 0.792
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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