Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
creb5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (495 aa)    
Predicted Functional Partners:
LOC113006738
V-fos FBJ murine osteosarcoma viral oncogene homolog Ab.
    
 0.981
fosl2
Fos-like antigen 2.
    
 0.978
atf2
Activating transcription factor 2.
    
  0.975
LOC113022570
Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.
    
  0.971
atf7
Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.
    
  0.971
LOC113026110
JunE proto-oncogene, AP-1 transcription factor subunit.
   
 0.960
ENSACLP00000018137
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.960
batf3
Basic leucine zipper transcription factor, ATF-like 3.
    
 
 0.957
LOC113021258
JunB proto-oncogene, AP-1 transcription factor subunit b.
   
 0.943
LOC113010449
JunD proto-oncogene, AP-1 transcription factor subunit.
   
 0.943
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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