Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
bub1bBUB1 mitotic checkpoint serine/threonine kinase Bb. (426 aa)    
Predicted Functional Partners:
ENSACLP00000006066
BUB3 mitotic checkpoint protein.
   
 0.999
ENSACLP00000030315
Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.999
ENSACLP00000008361
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.998
ENSACLP00000008418
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.998
cdc27
Cell division cycle 27.
    
 0.998
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
    
 0.998
ENSACLP00000028406
NDC80 kinetochore complex component.
   
 0.998
anapc10
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
    
 0.997
anapc4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.997
anapc5
Anaphase promoting complex subunit 5.
    
 0.997
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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