Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACLP00000005075ANK_REP_REGION domain-containing protein. (129 aa)    
Predicted Functional Partners:
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.770
ENSACLP00000017535
Serine/threonine-protein phosphatase.
   
 0.712
PPP6C
Serine/threonine-protein phosphatase.
   
 0.712
ENSACLP00000016397
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.641
LOC113036715
F-box and WD repeat domain containing 11b.
    
 0.604
traf7
TNF receptor-associated factor 7.
    
  0.601
LOC113008641
Protein phosphatase 6, regulatory subunit 2a.
    
 0.598
ppp6r3
Protein phosphatase 6, regulatory subunit 3.
    
 0.598
ppp6r2
Protein phosphatase 6, regulatory subunit 2b.
    
 0.598
ENSACLP00000018080
ANK_REP_REGION domain-containing protein.
  
 
 0.594
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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