STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000005132Pleckstrin and Sec7 domain containing a. (752 aa)    
Predicted Functional Partners:
gbf1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
     
0.816
arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited).
     
0.571
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited).
     
0.571
fbxo8
F-box protein 8.
     
 0.557
ENSACLP00000015237
IQ motif and Sec7 domain 2a.
     
0.556
iqsec1
IQ motif and Sec7 domain 1b.
     
0.556
iqsec3
IQ motif and Sec7 domain 3a.
   
 
0.548
LOC113024641
Cytohesin 4b.
     
0.540
ENSACLP00000031177
Cytohesin 4a.
   
 
0.524
CYTH3
Cytohesin 3.
     
0.522
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.