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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1219 aa)    
Predicted Functional Partners:
LOC113033130
Uncharacterized protein.
    
 0.913
LOC113025585
Guanine nucleotide binding protein (G protein), alpha 14.
    
 0.905
LOC113016248
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
    
 0.905
LOC113025584
Uncharacterized protein.
    
 0.905
LOC113015699
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.901
LOC113011723
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.901
GNA14
G protein subunit alpha 14.
    
 0.901
ENSACLP00000029412
Guanine nucleotide binding protein (G protein), alpha 14a.
    
 0.901
ENSACLP00000017448
Inositol 1,4,5-trisphosphate receptor, type 3.
    
 0.887
LOC113013785
Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family.
   
 
 0.881
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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