Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TMEM63BTransmembrane protein 63B. (844 aa)    
Predicted Functional Partners:
mri1
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
    
   0.540
copb1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
     
  0.496
galm
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
      
 0.492
snx15
Sorting nexin 15.
      
 0.485
tmem147
Transmembrane protein 147.
      
 0.463
LOC113026834
Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
  0.459
asns
Asparagine synthetase [glutamine-hydrolyzing].
      
 0.455
LOC113037120
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
     
 0.452
LOC113012470
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
     
 0.452
LOC113008528
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
     
 0.452
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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