Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113006880Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (321 aa)    
Predicted Functional Partners:
LOC113036936
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
     
 0.802
prkacb
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 0.755
LOC113011333
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 0.755
LOC113020616
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
   
 0.755
ENSACLP00000035547
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b.
   
 0.755
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
  
 0.734
LOC113025184
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.710
ENSACLP00000019390
Uncharacterized protein.
  
 
 0.687
aqp8
Aquaporin 8a, tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.681
LOC113028618
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.681
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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