Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000005359Uncharacterized protein. (356 aa)    
Predicted Functional Partners:
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.965
gdf15
TGF_BETA_2 domain-containing protein.
    
 
 0.961
ENSACLP00000014695
Neurturin.
    
 0.897
gdnf
Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.
    
 0.854
ENSACLP00000013020
Fibroblast growth factor receptor like 1a.
    
 0.738
fgfr3
Fibroblast growth factor receptor.
    
 0.738
ENSACLP00000023118
Fibroblast growth factor receptor 4; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.738
LOC113033119
Fibroblast growth factor receptor.
    
 0.738
ENSACLP00000029128
Uncharacterized protein.
    
 0.738
ENSACLP00000029170
Uncharacterized protein.
    
 0.738
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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