Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
snx10Sorting nexin 10b. (253 aa)    
Predicted Functional Partners:
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 0.909
ENSACLP00000016397
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.872
snx15
Sorting nexin 15.
     
 0.843
LOC113030809
Uncharacterized protein.
    
 0.803
vps26a
VPS26, retromer complex component A.
    
 0.803
vps26b
VPS26, retromer complex component B.
    
 0.803
rps6kc1
Ribosomal protein S6 kinase polypeptide 1.
     
 0.799
LOC113026417
PX domain-containing protein.
     
 0.602
LOC113035690
Sorting nexin 19b.
     
 0.597
LOC113010420
Wnt ligand secretion mediator.
    
 0.592
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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