Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aifm2Apoptosis inducing factor mitochondria associated 2. (371 aa)    
Predicted Functional Partners:
suox
Sulfite oxidase.
   
 0.902
tmlhe
Trimethyllysine hydroxylase, epsilon.
      
 0.892
cdkal1
CDK5 regulatory subunit associated protein 1-like 1.
     
 0.854
LOC113031405
Cytochrome b5 reductase 4.
    
 0.831
ggnbp2
Gametogenetin binding protein 2.
  
 
 0.820
LOC113018712
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.794
gsr
Glutathione reductase.
  
 0.752
ENSACLP00000038160
Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.
  
 
 0.751
ENSACLP00000007238
Uncharacterized protein.
     
 0.742
LOC113026005
Zgc:92275.
  
 
 0.714
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: high (90%) [HD]