Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACLP00000005399Dedicator of cytokinesis 1; Belongs to the DOCK family. (1887 aa)    
Predicted Functional Partners:
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.960
LOC113036661
CRK proto-oncogene, adaptor protein.
    
 0.955
LOC113030677
Uncharacterized protein.
    
 0.955
LOC113027161
Engulfment and cell motility 3.
    
 0.954
elmo2
Engulfment and cell motility 2.
    
 0.939
LOC113015157
Engulfment and cell motility 1.
    
 0.939
LOC113030686
Ras homolog family member Gb.
   
 0.893
LOC113030686-2
Rho-related GTP-binding protein RhoG-like.
   
 0.893
ENSACLP00000007513
Ras homolog gene family, member Gd.
   
 0.893
bcar1
BCAR1 scaffold protein, Cas family member.
    
 0.877
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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