Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000005409Salt-inducible kinase 1. (866 aa)    
Predicted Functional Partners:
ENSACLP00000011763
TORC_N domain-containing protein.
    
 0.948
ENSACLP00000011789
CREB regulated transcription coactivator 3.
    
 0.948
ENSACLP00000022436
TORC_N domain-containing protein.
    
 0.948
gins4
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
    
   0.898
rpl13
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
    
   0.823
LOC113036202
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.769
LOC113030401
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
    
 0.769
sik2
Salt-inducible kinase 2b.
   
  0.764
LOC113025499
1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
      
 0.723
rd3l
Uncharacterized protein.
      
 0.667
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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