Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM12ADAM metallopeptidase domain 12. (967 aa)    
Predicted Functional Partners:
adam17
ADAM metallopeptidase domain 17b.
     
 0.746
adam10
Uncharacterized protein.
     
 0.637
LOC113026622
ADAM metallopeptidase domain 10b.
     
 0.637
AXL
AXL receptor tyrosine kinase.
    
  0.637
ENSACLP00000038959
C-mer proto-oncogene tyrosine kinase a.
    
  0.637
LOC113023559
SH3 and PX domains 2Aa.
    
 0.536
SH3PXD2A
SH3 and PX domains 2A.
    
 0.536
sh3pxd2b
SH3 and PX domains 2B.
    
 0.530
LOC113020607
Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
      
 0.494
LOC113023863
Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
      
 0.494
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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