Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nedd4NEDD4 E3 ubiquitin protein ligase a. (1265 aa)    
Predicted Functional Partners:
LOC113014950
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.964
SGK1
Non-specific serine/threonine protein kinase.
    
 0.964
sgk2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.964
LOC113026105
Tyrosine-protein kinase receptor.
    
 0.941
igf1r
Tyrosine-protein kinase receptor.
    
 0.941
wwp1
WW domain containing E3 ubiquitin protein ligase 1.
    
 0.939
LOC113013680
E3 ubiquitin-protein ligase.
   
 0.938
LOC113021975
E3 ubiquitin-protein ligase.
   
 0.938
SMURF2
E3 ubiquitin-protein ligase.
    
 0.934
smurf1
E3 ubiquitin-protein ligase.
    
 0.934
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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