Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACLP00000005510Acetyl-coenzyme A synthetase. (677 aa)    
Predicted Functional Partners:
LOC113030206
Malate synthase-like.
  
 0.988
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.943
ENSACLP00000000637
Acetyl-CoA carboxylase beta.
  
 0.932
ENSACLP00000011952
Acetyl-CoA carboxylase alpha.
  
 0.932
pc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.929
acaa2
Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.927
acox3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 
 0.926
acox1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 
 0.924
hadhb
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.922
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.914
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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