pik3cg protein (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

pik3cg

Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1122 aa)

Predicted Functional Partners:

pik3r5

0.997

ENSACLP00000027490

0.977

ENSACLP00000018362

0.964

LOC113033441

0.961

ENSACLP00000011022

0.961

LOC113009053

0.961

pik3r1

0.961

PIP4K2B

0.953

gng2

0.952

GNG4

0.952

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000011022	ENSACLP00000018362	ENSACLP00000011022	ENSACLP00000018362	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Serine/threonine-protein kinase TOR.	0.923
ENSACLP00000011022	ENSACLP00000027490	ENSACLP00000011022	ENSACLP00000027490	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Uncharacterized protein.	0.836
ENSACLP00000011022	GNG4	ENSACLP00000011022	ENSACLP00000034643	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.807
ENSACLP00000011022	LOC113009053	ENSACLP00000011022	ENSACLP00000032720	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	0.544
ENSACLP00000011022	LOC113033441	ENSACLP00000011022	ENSACLP00000009076	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Uncharacterized protein.	0.932
ENSACLP00000011022	PIP4K2B	ENSACLP00000011022	ENSACLP00000013633	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.	0.857
ENSACLP00000011022	gng2	ENSACLP00000011022	ENSACLP00000003562	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.807
ENSACLP00000011022	pik3cg	ENSACLP00000011022	ENSACLP00000005516	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.961
ENSACLP00000011022	pik3r1	ENSACLP00000011022	ENSACLP00000039574	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).	0.549
ENSACLP00000011022	pik3r5	ENSACLP00000011022	ENSACLP00000008971	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphoinositide-3-kinase, regulatory subunit 5.	0.937
ENSACLP00000018362	ENSACLP00000011022	ENSACLP00000018362	ENSACLP00000011022	Serine/threonine-protein kinase TOR.	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	0.923
ENSACLP00000018362	LOC113009053	ENSACLP00000018362	ENSACLP00000032720	Serine/threonine-protein kinase TOR.	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	0.923
ENSACLP00000018362	LOC113033441	ENSACLP00000018362	ENSACLP00000009076	Serine/threonine-protein kinase TOR.	Uncharacterized protein.	0.931
ENSACLP00000018362	PIP4K2B	ENSACLP00000018362	ENSACLP00000013633	Serine/threonine-protein kinase TOR.	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.	0.490
ENSACLP00000018362	pik3cg	ENSACLP00000018362	ENSACLP00000005516	Serine/threonine-protein kinase TOR.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.964
ENSACLP00000018362	pik3r1	ENSACLP00000018362	ENSACLP00000039574	Serine/threonine-protein kinase TOR.	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).	0.923
ENSACLP00000027490	ENSACLP00000011022	ENSACLP00000027490	ENSACLP00000011022	Uncharacterized protein.	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	0.836
ENSACLP00000027490	GNG4	ENSACLP00000027490	ENSACLP00000034643	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.955
ENSACLP00000027490	LOC113009053	ENSACLP00000027490	ENSACLP00000032720	Uncharacterized protein.	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	0.836
ENSACLP00000027490	LOC113033441	ENSACLP00000027490	ENSACLP00000009076	Uncharacterized protein.	Uncharacterized protein.	0.836

page 1 of 5

Server load: medium (42%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About