Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000005517Cyclin L1a; Belongs to the cyclin family. (876 aa)    
Predicted Functional Partners:
cdk10
Cyclin-dependent kinase 10; Belongs to the protein kinase superfamily.
   
 
 0.903
LOC113013358
Cyclin-dependent kinase 11B.
   
 
 0.903
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
     
 0.856
ilf3
Interleukin enhancer binding factor 3b.
    
   0.836
ENSACLP00000021793
Uncharacterized protein.
    
   0.788
ENSACLP00000021816
Uncharacterized protein.
    
   0.788
ENSACLP00000033944
SAP30 binding protein.
    
   0.788
ENSACLP00000022919
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.783
gpatch2
G-patch domain-containing protein.
   
 
 0.781
ENSACLP00000021511
PRP40 pre-mRNA processing factor 40 homolog A.
   
   0.767
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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