Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC113008425Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family. (163 aa)    
Predicted Functional Partners:
rad18
RAD18 E3 ubiquitin protein ligase.
    
 0.957
trip12
Thyroid hormone receptor interactor 12.
    
 0.950
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.943
RPS27A
Ribosomal protein S27a.
    
 0.923
ENSACLP00000013723
E3 ubiquitin protein ligase.
    
 0.919
ENSACLP00000018578
E3 ubiquitin protein ligase.
    
 0.919
fancm
Uncharacterized protein.
    
 0.908
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.905
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 0.882
rad52
RAD52 homolog, DNA repair protein.
    
 0.881
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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