Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC113013092Rho GTPase activating protein 4a. (843 aa)    
Predicted Functional Partners:
ENSACLP00000012866
Uncharacterized protein.
    
 0.792
ENSACLP00000012873
SH3 domain-containing protein.
    
 0.792
ENSACLP00000014175
Intersectin 2b.
    
 0.792
nckipsd
NCK interacting protein with SH3 domain.
    
 
 0.639
ENSACLP00000000836
Intersectin 1 (SH3 domain protein).
    
 0.633
ENSACLP00000001080
Uncharacterized protein.
    
 0.633
ENSACLP00000012953
EH domain-containing protein.
    
 0.633
tsen2
tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...]
    
   0.590
LOC113008847
Uncharacterized protein.
   
 0.551
LOC113018881
Uncharacterized protein.
   
 0.551
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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