close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000005553RUN and FYVE domain containing 3. (468 aa)    
Predicted Functional Partners:
ENSACLP00000010328
Uncharacterized protein.
   
 
 0.846
ENSACLP00000009777
WDFY family member 4.
   
 
  0.836
uvrag
UV radiation resistance associated gene.
    
 0.814
LOC113034835
RUN and FYVE domain containing 1.
  
 
  
0.600
rab4a
RAB4a, member RAS oncogene family.
    
  0.600
rab4b
RAB4B, member RAS oncogene family.
    
  0.600
zc2hc1a
Zinc finger, C2HC-type containing 1A.
      
 0.538
ENSACLP00000026891
Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family.
     
 0.507
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 
 0.506
plekhm1
Pleckstrin homology domain containing, family M (with RUN domain) member 1.
     
 0.498
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.