Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmem39bTransmembrane protein 39B. (489 aa)    
Predicted Functional Partners:
ENSACLP00000010921
Uncharacterized protein.
      
 0.655
ENSACLP00000010998
Phospholipase D family, member 6.
      
 0.609
ENSACLP00000014386
SEC63 homolog, protein translocation regulator.
      
 0.603
LOC113031177
DnaJ (Hsp40) homolog, subfamily C, member 18.
      
 0.546
rhbdd3
Rhomboid domain containing 3.
      
 0.543
hgh1
HGH1 homolog (S. cerevisiae).
      
 0.468
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
      
 0.465
prcc
Proline rich mitotic checkpoint control factor.
      
 0.428
LOC113027814
Zgc:112185.
      
 0.423
trmt112
tRNA methyltransferase subunit 11-2.
      
 0.423
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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