Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ing1Inhibitor of growth protein. (306 aa)    
Predicted Functional Partners:
LOC113026940
SIN3-HDAC complex associated factor.
    
 
 0.940
LOC113018712
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.932
suds3
SDS3 homolog, SIN3A corepressor complex component.
    
 
 0.906
ENSACLP00000034796
Translocase of outer mitochondrial membrane 20.
   
 0.901
LOC113006594
BRMS1 like transcriptional repressor b.
    
 
 0.894
LOC113018594
BRMS1 transcriptional repressor and anoikis regulator.
    
 
 0.880
sap30l
Sap30-like.
    
 
 0.878
meaf6
MYST/Esa1-associated factor 6.
    
 0.860
ENSACLP00000015681
Uncharacterized protein.
   
 
 0.855
phf20
PHD finger protein 20, a.
   
 
 0.855
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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