Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113008948Aurora kinase B; Belongs to the protein kinase superfamily. (331 aa)    
Predicted Functional Partners:
ENSACLP00000018315
Uncharacterized protein.
   
 0.994
LOC113028579
Baculoviral IAP repeat containing 5a.
   
 0.992
cdca8
Cell division cycle associated 8.
   
 0.991
ENSACLP00000003678
TPX2 microtubule nucleation factor.
   
 0.989
LOC113013372
Baculoviral IAP repeat containing 5b.
   
 0.982
ENSACLP00000028406
NDC80 kinetochore complex component.
   
 
 0.982
ENSACLP00000002644
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.976
LOC113018712
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.960
bora
Bora aurora kinase A activator.
   
 0.954
ENSACLP00000018777
Cytoplasmic polyadenylation element binding protein 1b.
   
 0.952
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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