Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nfx1Nuclear transcription factor, X-box binding 1. (1066 aa)    
Predicted Functional Partners:
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 0.899
LOC113016095
Ubiquitin protein ligase E3A.
    
 0.847
LOC113012058
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
     
  0.841
LOC113023515
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
     
  0.841
RPL7A
Ribosomal protein L7a.
    
 
 0.785
ENSACLP00000014023
Ribosomal protein L17; Belongs to the universal ribosomal protein uL22 family.
    
   0.765
rpl13a
Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
    
   0.765
ENSACLP00000020299
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
    
   0.755
rps5
Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.
    
   0.732
ENSACLP00000011733
Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
    
   0.732
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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