Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
urosUroporphyrinogen III synthase. (261 aa)    
Predicted Functional Partners:
hmbs
Hydroxymethylbilane synthase a.
  
 0.995
alad
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 0.995
urod
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.989
ENSACLP00000007618
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.951
ENDOV
Endonuclease V.
  
 
 0.916
fech
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
  
 0.888
iyd
Iodotyrosine deiodinase.
  
 
 0.858
bccip
BRCA2 and CDKN1A interacting protein.
   
  
 0.744
ENSACLP00000026500
Zinc finger protein.
    
 
 0.743
LOC113016274
Coproporphyrinogen oxidase.
     
 0.732
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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