Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
slc66a1lUncharacterized protein. (311 aa)    
Predicted Functional Partners:
slc66a1
Solute carrier family 66 member 1.
     
 0.877
spr
Sepiapterin reductase b.
    
  0.866
pts
6-pyruvoyltetrahydropterin synthase.
     
  0.854
LOC113028261
GTP cyclohydrolase 2.
     
  0.812
gch1
GTP cyclohydrolase 1.
     
  0.812
bckdha
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
     
  0.718
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
     
  0.718
alpl
Alkaline phosphatase.
     
  0.626
ENSACLP00000021633
Alkaline phosphatase.
     
  0.626
LOC113037657
Alkaline phosphatase, intestinal, tandem duplicate 2; Belongs to the alkaline phosphatase family.
     
  0.626
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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