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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrrc1Leucine rich repeat containing 1. (680 aa)    
Predicted Functional Partners:
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 0.888
ENSACLP00000020107
Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.
    
 0.877
LOC113016095
Ubiquitin protein ligase E3A.
    
 0.861
llgl2
LLGL scribble cell polarity complex component 2.
    
 0.853
LLGL1
LLGL scribble cell polarity complex component 1.
    
 0.853
ENSACLP00000001953
Adhesion G protein-coupled receptor L2a; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.766
LOC113011391
Si:ch1073-186i23.1; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.766
adgrl1
Adhesion G protein-coupled receptor L1a; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.766
LOC113010089
Vav 3 guanine nucleotide exchange factor b.
    
 0.765
ntng1
Netrin g1a.
    
 0.765
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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