Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lrrc1Leucine rich repeat containing 1. (680 aa)    
Predicted Functional Partners:
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 0.956
LOC113016095
Ubiquitin protein ligase E3A.
    
 0.915
llgl2
LLGL scribble cell polarity complex component 2.
    
 0.906
LLGL1
LLGL scribble cell polarity complex component 1.
    
 0.906
ENSACLP00000020107
Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.
    
 0.903
LOC113030203
Discs, large homolog 4a (Drosophila); Belongs to the MAGUK family.
    
 0.836
ENSACLP00000027470
Uncharacterized protein; Belongs to the MAGUK family.
    
 0.836
ENSACLP00000028183
Discs, large homolog 3 (Drosophila); Belongs to the MAGUK family.
    
 0.836
ENSACLP00000028400
Si:dkey-31j3.11.
    
 0.836
LOC113010204
Discs, large (Drosophila) homolog 1, like; Belongs to the MAGUK family.
    
 0.836
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (22%) [HD]