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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113022617Premelanosome protein a. (767 aa)    
Predicted Functional Partners:
MLANA
Uncharacterized protein.
   
  
 0.954
TYR
Tyrosinase.
   
 
 0.934
ENSACLP00000024801
Ig-like domain-containing protein.
    
   0.878
LOC113012896
BHLH domain-containing protein.
    
 0.816
ENSACLP00000031402
Transcription factor binding to IGHM enhancer 3b.
    
 0.816
mitf
Melanocyte inducing transcription factor a.
    
 0.796
slc24a5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
  
 0.738
tyrp1
Tyrosinase related protein 1.
   
 
 0.733
ENSACLP00000017239
Tyrosinase-related protein 1b.
   
 
 0.718
dct
Dopachrome tautomerase.
   
 
 0.712
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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