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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000005764Collagen IV NC1 domain-containing protein. (1499 aa)    
Predicted Functional Partners:
LOC113022754
Tankyrase_bdg_C domain-containing protein.
    
  0.650
itgb5
Integrin beta; Belongs to the integrin beta chain family.
    
 0.638
itgb1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.634
LOC113010138
Integrin beta; Belongs to the integrin beta chain family.
    
 0.633
ENSACLP00000031964
Integrin beta; Belongs to the integrin beta chain family.
    
 0.631
ENSACLP00000033830
Integrin beta.
   
 0.630
itgb8
Integrin beta; Belongs to the integrin beta chain family.
    
  0.628
itga8
Integrin, alpha 8; Belongs to the integrin alpha chain family.
    
 0.624
ENSACLP00000013746
Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2; Belongs to the integrin alpha chain family.
   
 
 0.612
itga1
Integrin, alpha 1; Belongs to the integrin alpha chain family.
     
 0.610
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.