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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000005785PDZ domain-containing protein. (679 aa)    
Predicted Functional Partners:
ENSACLP00000005819
Uncharacterized protein.
 
      0.803
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 0.708
LOC113014387
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
 0.708
LOC113032794
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
 0.708
apc2
APC regulator of WNT signaling pathway 2.
    
 0.668
ENSACLP00000028674
APC_N_CC domain-containing protein.
    
 0.668
ENSACLP00000028679
APC regulator of WNT signaling pathway.
    
 0.668
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
    
 0.659
dvl2
Dishevelled segment polarity protein 2.
   
 0.655
dvl3
Dishevelled segment polarity protein 3a.
   
 0.655
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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