Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113022620Advillin. (818 aa)    
Predicted Functional Partners:
cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 
 0.737
ENSACLP00000034439
Phosphoinositide kinase, FYVE finger containing.
     
  0.736
ENSACLP00000010243
Component of oligomeric golgi complex 3.
    
 
 0.729
ENSACLP00000036802
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
    
 
 0.655
ENSACLP00000036839
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
    
 
 0.655
LOC113008847
Uncharacterized protein.
    
 
 0.639
LOC113026240
WASP like actin nucleation promoting factor a.
    
 
 0.639
cog4
Component of oligomeric golgi complex 4.
    
 
 0.630
smim7
Small integral membrane protein 7.
    
 
 0.630
get3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
   
   0.614
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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