osbpl3 protein (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

osbpl3

Oxysterol-binding protein; Belongs to the OSBP family. (850 aa)

Predicted Functional Partners:

gak

0.754

vapa

0.648

ENSACLP00000031727

0.648

LOC113013172

0.611

ENSACLP00000002940

0.595

casp9

0.532

apaf1

0.532

LOC113017771

0.525

mospd1

0.525

ndufa12

0.510

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000002940	gak	ENSACLP00000002940	ENSACLP00000028221	DnaJ (Hsp40) homolog, subfamily C, member 6.	Cyclin G associated kinase.	0.995
ENSACLP00000002940	osbpl3	ENSACLP00000002940	ENSACLP00000005898	DnaJ (Hsp40) homolog, subfamily C, member 6.	Oxysterol-binding protein; Belongs to the OSBP family.	0.595
ENSACLP00000031727	osbpl3	ENSACLP00000031727	ENSACLP00000005898	VAMP (vesicle-associated membrane protein)-associated protein B and C.	Oxysterol-binding protein; Belongs to the OSBP family.	0.648
LOC113013172	osbpl3	ENSACLP00000031473	ENSACLP00000005898	MSP domain-containing protein.	Oxysterol-binding protein; Belongs to the OSBP family.	0.611
LOC113017771	osbpl3	ENSACLP00000008619	ENSACLP00000005898	MSP domain-containing protein.	Oxysterol-binding protein; Belongs to the OSBP family.	0.525
apaf1	casp9	ENSACLP00000032714	ENSACLP00000026306	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.999
apaf1	ndufa12	ENSACLP00000032714	ENSACLP00000023035	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.562
apaf1	osbpl3	ENSACLP00000032714	ENSACLP00000005898	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Oxysterol-binding protein; Belongs to the OSBP family.	0.532
casp9	apaf1	ENSACLP00000026306	ENSACLP00000032714	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.999
casp9	osbpl3	ENSACLP00000026306	ENSACLP00000005898	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Oxysterol-binding protein; Belongs to the OSBP family.	0.532
gak	ENSACLP00000002940	ENSACLP00000028221	ENSACLP00000002940	Cyclin G associated kinase.	DnaJ (Hsp40) homolog, subfamily C, member 6.	0.995
gak	osbpl3	ENSACLP00000028221	ENSACLP00000005898	Cyclin G associated kinase.	Oxysterol-binding protein; Belongs to the OSBP family.	0.754
mospd1	osbpl3	ENSACLP00000034350	ENSACLP00000005898	Motile sperm domain containing 1.	Oxysterol-binding protein; Belongs to the OSBP family.	0.525
ndufa12	apaf1	ENSACLP00000023035	ENSACLP00000032714	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.562
ndufa12	osbpl3	ENSACLP00000023035	ENSACLP00000005898	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	Oxysterol-binding protein; Belongs to the OSBP family.	0.510
osbpl3	ENSACLP00000002940	ENSACLP00000005898	ENSACLP00000002940	Oxysterol-binding protein; Belongs to the OSBP family.	DnaJ (Hsp40) homolog, subfamily C, member 6.	0.595
osbpl3	ENSACLP00000031727	ENSACLP00000005898	ENSACLP00000031727	Oxysterol-binding protein; Belongs to the OSBP family.	VAMP (vesicle-associated membrane protein)-associated protein B and C.	0.648
osbpl3	LOC113013172	ENSACLP00000005898	ENSACLP00000031473	Oxysterol-binding protein; Belongs to the OSBP family.	MSP domain-containing protein.	0.611
osbpl3	LOC113017771	ENSACLP00000005898	ENSACLP00000008619	Oxysterol-binding protein; Belongs to the OSBP family.	MSP domain-containing protein.	0.525
osbpl3	apaf1	ENSACLP00000005898	ENSACLP00000032714	Oxysterol-binding protein; Belongs to the OSBP family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.532