Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACLP00000005908Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2462 aa)    
Predicted Functional Partners:
LOC113030095
Rap guanine nucleotide exchange factor (GEF) 6.
    
 0.893
ENSACLP00000022985
Uncharacterized protein.
    
 
 0.816
pdlim4
PDZ and LIM domain 4.
    
 0.789
ENSACLP00000017769
Rap guanine nucleotide exchange factor (GEF) 2.
    
   0.787
ENSACLP00000002621
Si:ch211-204d2.4.
    
  0.667
map3k2
Mitogen-activated protein kinase kinase kinase 2.
    
 
 0.663
LOC113018242
PH domain-containing protein.
    
 0.649
gab1
GRB2-associated binding protein 1.
    
 0.649
LOC113027966
Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b.
    
  0.627
apc2
APC regulator of WNT signaling pathway 2.
    
   0.613
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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