Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gsdmeGasdermin Eb. (476 aa)    
Predicted Functional Partners:
casp7
Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.964
ENSACLP00000029912
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.931
LOC113027421
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.931
ENSACLP00000030320
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.931
LOC113027422
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.931
ENSACLP00000029815
Caspase 3; Belongs to the peptidase C14A family.
    
 0.929
ENSACLP00000030061
Caspase 3; Belongs to the peptidase C14A family.
    
 0.929
LOC113024393
Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.
    
 0.929
LOC113014732
Uncharacterized protein.
     
  0.872
ENSACLP00000024870
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.869
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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